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Abstract the prohormone convertases (pc) 1/3 and 2 are calcium-activated eukaryotic subtilisins with low ph optima which accomplish the limited proteolysis Buy brain natriuretic peptide, pro, aa1-108, recombinant, human (probnp, prohormone brain natriuretic pe, item number: b2702-03c. 10 from united states. During catheterization we measured the levels of plasma n-terminal atrial natriuretic peptide prohormone in the plasma of 68 children with congenital heart. Background: the prohormone of b-type natriuretic peptide (probnp1-108) is a 108-amino acid peptide produced primarily by the heart and cleaved into. B-type natriuretic peptide (bnp) is a hormone produced by your heart. N-terminal (nt)-pro hormone bnp (nt-probnp) is a non-active prohormone. A prohormone is a committed precursor of a hormone consisting of peptide hormones synthesized together that has a minimal hormonal effect by itself because. Peptide biosynthesis: prohormone convertases 1/3 and 2. 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